Heliot Ramos, Rafael Devers and Wilmer Flores homered off Nestor Cortes in the first inning and the San Francisco Giants beat San Diego 4-3 on Monday night to hand the Padres their fourth straight loss.

Ramos showed how much he wants Melvin to stick around Monday night, hitting a lead-off homer that sparked a 4-3 win over the host San Diego Padres in the opener of a four-game series. Ramos and the Giants will try to make it two wins in a row over San Diego on Tuesday night.

The San Francisco Giants and the San Diego Padres play the second contest of a 4-game series at Petco Park in San Diego.

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Robbie Ray (9-6, 2.98 ERA, 1.14 WHIP, 152 strikeouts); Padres: Nestor Cortes (1-1, 5.71 ERA, 1.56 WHIP, 17 strikeouts) BOTTOM LINE: The San Diego Padres host the San Francisco Giants to open a four-game series.