The Kansas City Chiefs officially know what lies ahead for their 2025 campaign after the NFL released its full regular season schedule on Wednesday, May 14. As the defending AFC champions, the Chiefs will face high expectations throughout the season and may even face headwinds in their preseason exhibition matchups this summer.

Here’s the full Chiefs 2025 schedule: Friday, Aug. 22: Chicago, 7:20 p.m., Channel 41 Friday, Sept. 5: at L.A. Chargers (in Sao Paulo, Brazil), 7 p.m., YouTube Sunday, Sept. 14: Philadelphia, 3:25 p.m., FOX Sunday, Sept. 21: at New York Giants, 7:20 p.m., NBC Sunday, Sept. 28: Baltimore, 3:25 p.m., CBS

Along with the opening international game, the Chiefs will take on the Cowboys on Thanksgiving Day (Week 13) and will also host a Christmas Day game against the Denver Broncos on December 25. The NFL announced the full schedules for all 32 teams on Wednesday. Here is the Chiefs’ outlook for 2025.